Question #1acbb

1 Answer
Nov 8, 2015

Because you needs the electrons of the ring to attack the acyl or alkyl molecule.

Explanation:

The Friedel Crafts reactions it's an electrophilic aromatic substitution, so the group that is going to replace the hydrogen in the ring(the alkyl or acyl halide) is looking for electrons. When you put a deactivating group in the ring, this group is taking away the electrons from the ring and it's harder for the alkyl or acyl group to perform the reaction. In the case of a basic group, I think it's because the catalyst #AlCl_3# it's a strong lewis acid so it can react with the basic group before the main reaction takes place.