Question

Why is phosphorylation favorable?

Answer 1

Phosphorylation plays a critical role in the regulation of many cellular processes including cell cycle, growth, apoptosis and signal transduction pathway.

Explanation:

Phosphorylation allows coupling and addition of a phosphoryl group. In biology phosphorylation and dephosphorylation are critical for many cellular processes. It is the most common mechanism of regulating protein function and transmitting signals throughout the cell.

Phosphorylation is especially important for protein function as this modification activates or deactivates almost half of the enzymes, thereby regulating their function. Protein phosphorylation is considered the most abundant post translational modification in eukaryotes. Phosphorylation of sugars is often the first stage of their catabolism.