First of all, let's compute the derivative of #f(x)#, indicated as #f'(x)#:
#f(x) = -x^3-3 \implies f'(x) = -3x^2#
In fact, to derive a sum you must derive each single term. The first term is a power of #x#, and the derivative of #x^n# is #nx^{n-1}#. So, the derivative of #x^3# is #3x^{3-1} = 3x^2#, and since we had a minus sign in front of it, we will have to change signs: the derivative of #-x^3# is #-3x^{3-1} = -3x^2#.
As for the second term, the derivative of a number is always zero, which is why the term #-3# has disappeared in the derivative.
Now, just like our function #f(x)# associated a #y# with every #x#, in the same way our derivative #f'(x)# associates, for every point #x#, the slope of the line tangent to the graph in the point #(x,f(x))#
In other words, #f'(-1)# is exactly the answer you are looking for. The computation is
#f'(-1) = -3(-1)^2 = -3\cdot 1 = -3#