How could #H_3CH_2COCH_2CH_2CH_3# be made?

1 Answer
anor277
May 16, 2017

Well, you could mix ethyl bromide with propanol in the presence of a non-nucleophilic base...........

Explanation:

And thus, we could write the stoichiometric reaction:

#EtBr + HOPr + DBU +Deltararr Et-O-Pr+DBU*HCl#

#"DBU"# and #"DABCO"# are non-nucleophilic bases that would be added in stoichiometric quantity; alternatively, #Et_3N# could be used as the base. Would it work? Got me. At least your starting materials are plentiful so you could afford to experiment.

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