Question #e6b23
1 Answer
Jul 29, 2017
Here's one possible sequence.
Explanation:
Step 1. Allylic bromination with N-bromosuccinimide
This is also known as the Wohl-Ziegler reaction.
It is a free radical reaction, and bromination occurs preferentially at the secondary carbon because the corresponding intermediate radical is better stabilized.
Step 2. Anti-Markovnikov addition of
This is a free radical addition, not a substitution.
Step 3. Intramolecular Wurtz reaction
This method gives good yields of cyclopropanes.