How do you know which mixture of products are favoured when phenol is brominated?

1 Answer
Jan 21, 2018

How else but by measurement...? Do the reaction, and assess the results.

Explanation:

I presume you refer to electrophilic aromatic substitution of phenols. Now the hydroxyl substitution activates all positions on the ring; it especially activates the ortho and para positions. Specific conditions might be found to give ortho or para substitution...treatment of phenol with bromine would likely give #"1,3,5-tribromophenol"#.