Question

Question #70cda

Answer 1

Proteins (such as most enzymes), denature (get permanently destroyed) when the pH is inadequate (such as with enzymes) or the temperature is too high.

Explanation:

When proteins denature, they lose their structural shape/molecular structure.

Enzymes all have particular shapes and all work best at specific temperatures and pHs. Enzymes in the stomach, for example, often work best at a pH of 2-2.4 because the stomach is very acidic. (The lower the pH, the more acidic.) Denatured enzymes can no longer perform their required tasks.

One of the body's immune responses to pathogens is to raise the temperature (fever) to hopefully denature the invading pathogen's enzymes.

For more help:
http://chemistry.elmhurst.edu/vchembook/568denaturation.html