# cos (arcsin (-3/5))#
#sin^{-1}(x)#, which I prefer to denote #arcsin(x)#, refers to every inverse sine, not just the principal value, which I denote #text{Arc}text{sin}(x).#
#cos theta# where #theta = arcsin(-3/5) #
#sin theta = -3/5#
Of course #3^2 + 4^2 = 5^2 # is everybody's favorite Pythagorean Triple.
#cos ^2 theta + sin ^2 theta = 1 #
# cos ^2 theta = 1 - sin ^2 theta #
#cos theta = pm sqrt{1 - sin ^2 theta }#
#cos theta = \pm sqrt{1 - (-3/5)^2} = pm sqrt{1-9/25}= pm sqrt{16/25} = pm 4/5 #
#cos (arcsin (-3/5)) = \pm 4/5#
The sign cannot be determined with the information given.