How does apoptosis programmed cell death occur in fetal development?
Folicular atresia in ovaries is also a result of PCD (Programmed Cell Death). A human fetus has webbed hands and feet early on its development. Later, apoptosis removes skin cells, revealing individual fingers and toes. A fetus's eyelids form an opening by the process of apoptosis.
An exaggerated PCD or a defective apoptosis during embryogenesis may cause developmental abnormalities.