How does aspirin help to reduce clotting? Does it reduce the red blood count, reduce platelet aggregation, reduce the platelet count, bind to fibrin, or inhibit thrombin?

1 Answer
Apr 1, 2016

Reduce Platelet Aggregation


Thromboxane A2 (TXA2) is a chemical that is produced from cell membrane Phospholipid, and increases platelet aggregation inside blood vessels.

Aspirin reduces the TXA2 production from membrane phospholipid by blocking COX-1 enzyme.

We have seen that Thromboxane A2 (TXA2) increases platelet aggregation. And aspirin decreases the production of TXA2. As a result aspirin decreases platelet aggregation and thus help to reduce clotting.