How does pH affect amino acid charge?

1 Answer
Jul 31, 2017

Protonation and deprotonation of the functional groups


I explained this in a duplicate question. Here is the link to that.
How does pH affect amino acid structure?

Summary of the explanation is that you look at the #pK_a# values of the carboxyl and amino groups of the generic structure. Some R groups may be protonated, so pay attention to those. Depending on the pH that your amino acid is at, certain groups may or may not be protonated.

Hope this helps!