How is ATP hydrolysis reaction a coupling process?
The hydrolysis of
The process is highly favourable, so it happens spontaneously.
Many enzymes can use the free energy released by the hydrolysis of
This process is
For example, the conversion of glucose to glucose-6-phosphate is thermodynamically unfavourable.
The enzyme hexokinase brings these two reactions together, so that the energy released by the hydrolysis of
The reactions are
The coupled reaction has a negative free energy, so the process is thermodynamically favourable.