What covalent bond links nucleotides together?

1 Answer
Jul 2, 2015

The covalent bond that links nucleotides in the sugar-phosphate backbone is a phosphodiester bond.


Nucleotides are linked together by the formation of a phosphodiester bond which is formed between the 3' -OH group of one sugar molecule, and the 5' phosphate group on the adjacent sugar molecule. This results in a loss of a molecule of water, making this a condensation reaction, also called a dehydration synthesis.