What do clotting proteins include?
There are thirteen clotting factors.
The factors are in order:
III. Tissue thromboplastin
IV. Calcium ions (
V. Proaccelerin (labile factor)
VI. Not known
VII. Proconvertin (stable factor)
VIII. Antihaemophilic factor A
IX. Antihaemophilic factor B (Christmas factor)
X. Stuart-Prower factor
XI. Plasma thromboplastin antecedent
XII. Hageman factor
XIII. Fibrin stabilizing factor
All these factors work as a system to cause clotting of blood.
Clotting is essentially a cascade of enzymes which we describe as clotting factors. Deficiency of any one of these causes blood clotting not to occur.
Very common examples are hemophilia A and hemophilia B which are caused because of the impairment of clotting factors VIII and IX, respectively.