What happens if microtubules and microfilaments are absent in the cell?
Some microtubules are using in protein transport (by kinesin and dynein). Even organelles like mitochondria is transported via microtubule network. So protein transport and organelle movement will get disrupted
For example, when nocodazole was used to disrupt microtubules,
directional mitochondrial motility was impaired
Florian Fuchs (2002) Interaction of mitochondria with microtubules in the filamentous fungus Neurospora crassa
Mariusz Karbowski, et. al., (2000) Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells