What is oxidative phosphorylation?
Oxidative phosphorylation is the metabolic pathway in which the mitochondria in cells use the energy released by the oxidation of nutrients to synthesize ATP.
Here is a highly condensed summary of the process.
Stage 1 is glycolysis.
Glycolysis is a 10-step pathway. The overall reaction is
Stage 2 is oxidative decarboxylation.
The overall equation is
The essential feature is that
The NADH then heads off to the electron transport chain to help create more ATP, and the acetyl-CoA enters the Tricarboxylic Acid Cycle.
Stage 3 is the Tricarboxylic Acid Cycle
The Tricarboxylic Acid Cycle is a series of eight reactions that occur in the inner layer of the mitochondrion.
They completely oxidize acetate to carbon dioxide.
The overall equation is:
The energy is produced is stored in
Stage 4 is the Electron Transport Chain
As the hydrogen ions flow, ATP is made from ADP and phosphate ions.
The net reaction is:
In total, one glucose molecule yields about 32 ATP molecules by oxidative phosphorylation.
Oxidative phosphorylation accounts for around 90 % of the body's total ATP.
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