What is the difference between acetoacetate , acetyl-CoA , and acetoacetyl-CoA?

1 Answer
May 6, 2017

Here's what I get.

Explanation:

Acetoacetate

Acetate is the carboxylate ion of acetic acid.

Acetate

In acetoacetate, an α-hydrogen has been replaced by an aceto or acetyl group, #"CH"_3"CO"#.

Acetoacetate

Acetyl-CoA

Acetyl-CoA is Coenzyme A in which the #"H"# atom in the thiol group has been replaced by an acetyl group.

This is Coenzyme A:

upload.wikimedia.org

And this is acetyl-CoA:

Acetyl-CoA
(From Wikipedia)

Acetoacetyl-CoA

Acetoacetyl-CoA is Coenzyme A in which the #"H"# atom in the thiol group has been replaced by an acetoacetyl group, #"CH"_3"COCH"_2"CO"#.

Acetoacetyl-CoA
(From Wikipedia)