Question

What is the effect of exposure to UV rays on the skin?

Answer 1

Ultra Violet (UV) irradiation present in sunlight is an environmental human carcinogen.

Explanation:

The major acute effects of UV irradiation on normal human skin comprise sunburn inflammations ( erythema) tanning and local or systemic immunosuppression .

At the molecular level, UV irradiation causes DNA damage , which are usually repaired by nucleotide excision repair.

Chronic exposure to UV repair leads to photo aging , immunosuppression and photocarcinogenesis.

Photocarcinogenesis involves the accumulation of genetic changes, as well as immune system modulation and ultimately leads to the development of skin cancers.