Question

What would you do if you discovered a material with positively charged electrons, and a negatively charged nucleus?

Answer 1

I think I would call the `"National Enquirer..........."`

Explanation:

And announce that I have discovered `"antimatter"`.

The proposition you are making is hard to rationalize. What's an atom? As far as anyone knows, it's a collection of fundamental particles, some massive and some not, and some of the massive particles have an opposite electronic charge to the particles of negligible mass. So if you have got some stuff that is not composed of protons and electrons and neutrons, there is not much to which you could compare it. It's outside the rationale of a chemist, and perhaps also outside the ken of a physicist.

Anyway, look at this site, and see if it can give some ideas.