What is the RNA interface?

1 Answer
Aug 20, 2017

RNA interference is a biological process in which RNA molecules, inhibit gene expression or translation by neutralising targeted mRNA molecules.


RNA interference has an important role in defending cells against parasitic nucleotide sequences - viruses and transposons. It also influences development.

RNA interference is a natural process that cells use to turn off or silence unwanted or harmful genes. In natural RNA interference dsRNA in the cell's cytoplasm is cut by an enzyme into ds interfering RNA molecules. This small interfering RNA binds to an RNA induced silencing complex (RISC) which separates the two strands into the passenger and guide strand. The passenger strand is degraded and the RISC takes the guide strand to a specific mRNA site, cleaving it so that the unwanted target protein is not produced. This is how the gene is silenced.