Question

What research has been done on mitochondrial granules?

Answer 1

Since their discovery in the early fifties, mitochondrial granules have been subject to many researches.

Explanation:

Mitochondrial matrix granules are particles containing phospholipids, proteins and calcium found in the mitochondria.

Twenty years ago, two hypotheses on their functions were introduced:

1) the granules were considered as sinks for cations and that they regulated the concentrations of these ions (Peachey).

2) they were considered to be precursors of the mitochondrial inner membrane (Barnard).

In heart muscle in stimulating situations, the native matrix granules move towards the inner membrane and are incorporated in it. They appear to create contact sites between inner and outer mitochondrial membranes in which enzymes can function efficiently.