A deficiency of which vitamin can lead to macrocytic anemia?

1 Answer
Linica Uday
Jan 17, 2017

The spectrum of etiologies associated with macrocyctic anemia includes B12 or folate vitamin deficiency, drug disorders and other chronic illness.

Explanation:

Macrocytosis due to vitamin B12 or folate deficiency is a direct result of ineffective or dysplastic erythropoesis. These important vitamins and co factor are required for normal maturation of all cells. During this condition erythroblasts become large , oval shaped and contain a characteristic immature lacy nucleus.

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