# Are the H2O molecules are too large to pass between the phospholipids while the molecules of CO2 and O2 are not?

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Al E. Share
Feb 24, 2018

I wouldn't call a water molecule large in relation to $C {O}_{2}$ and ${O}_{2}$.

I would call them polar, though,

The polarity of these molecules makes it very hard to pass through the largely hydrophobic interior of the phospholipid bilayer,

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