Question

How can disruption of the cell cycle result in cancer?

Answer 1

Cell cycle continues in a highly regulated manner: when the regulation is disrupted, the cycle progresses in an uncontrolled way resulting in cancer.

Explanation:

Cancer is called a malignant neoplasm. Neoplasm is a newly grown abnormal mass of tissue. Malignancy is a condition when cells continue to divide despite overcrowding which a normal cell will never do.

There are several check points in cell cycle when a cell may recognise damage and thus may proceed to disintegrate itself which is termed apoptosis. All such capabilities of a normal cell are lost in the malignant one.