Question

How does a bacteria like Cholera cause diarrhea?

Answer 1

In Cholera toxin, the A subunit acts on adenylate cyclase+G-protein unit located on the membrane . This causes more AMP to be converted to cAMP (cyclic AMP). This cause dramatic efflux of ions and water from infected enterocytes, leading to watery diarrhoea.

Explanation:

Read more:
https://www.ebi.ac.uk/interpro/potm/2005_9/Page2.htm

https://books.google.com.my/books?id=K1jKUUKDanQC&pg=PA201&lpg=PA201&dq=bacteria+toxin+on+sodium+pump&source=bl&ots=ta5erxtqKg&sig=4q5A-_Yqlr66G3SSJq5WaOU3nr8&hl=en&sa=X&redir_esc=y#v=onepage&q=bacteria%20toxin%20on%20sodium%20pump&f=false

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089049/?report=reader