Is the outer surface of a nerve impulse normally negative and the inner part usually positive?

1 Answer
Jun 13, 2016

No. When a neuron is not carrying an impulse, the inside of the axon is negative and the outside is positive.

Explanation:

The cell membrane has a different permeability for different ions.

1. A process called the sodium-potassium pump uses ATP to pump out three #"Na"^+# ions and pump in two #"K"^+# ions.

2. The membrane has ion channels that allow #"K"^+# ions to pass through to the interior of the cell while blocking #"Na"^+# ions.

3. Negatively charged proteins inside the cell cannot pass through the membrane.

In the resting state, these three mechanisms make the inside of the membrane more negative than the outside by about -70 mV.

The diagram below shows a resting neuron. The + signs represent cations and the - signs represent anions.

Membrane potential
(From www.apsubiology.org)

The video below shows how the membrane potential is generated and maintained by using the sodium-potassium pump and potassium channels.