What are integrin #alpha# and #beta# in biology?

1 Answer
Nov 22, 2015

Integrin is a family of membrane proteins composed of heterodimers with α and β subunits.


Integrins have a major role in integrating extracellular and intracellular environments. Another role is adhesion of cells to their substratum or other cells.

Integrins exist as two non-covalently bound a and b subunits, which
pair to form heterodimers. They function as adhesion molecules and play key roles in actin cytoskeleton organization and transduction of intracellular signals.