What is hydroboration oxidation?

1 Answer
Apr 15, 2018

It's a hydration reaction that exhibits syn stereochemistry and anti-Markovnikov regiochemistry.

If our substrate is an alkene, we added a hydride and #BH_2# group concertedly. Next, we do an oxidative workup (which is rather complicated), to ultimately replace the #BH_2# with a hydroxyl group.

puu.sh

The enantiomer (or diastereomer) is included because the addition is taking place concertedly on a planar substrate (e.g. alkene).