We first need to work the derivative of csc^-1(x)
We can start with this:
y = csc^-1(x) -> csc(y)=x
Now differentiate both sides implicitly with respect to x to get:
-dy/dxcsc(y)cot(y)=1
-> dy/dx = -1/(csc(y)cot(y))
Now, using:
sin^2(y)+cos^2(y)=1
Divide this identity through by sin^2(y) to get:
1+cot^2(y)=csc^2(y) -> cot(y) = sqrt(csc^2(y)-1)
We can now plug this into our equation for dy/dx to get:
dy/dx = -1/(csc(y)sqrt(csc^2(y)-1)
Using csc(y)=x we may now rewrite dy/dx in terms of x:
dy/dx = -1/(xsqrt(x^2-1)
So now that we have the derivative of csc^(-1)x we can now apply the chain rule to obtain the derivative of y=csc^-1(4x^2)
-> dy/dx= -1/((4x^2)sqrt((4x^2)^2-1)).d/dx(4x^2)
=-(8x)/((4x^2)sqrt((4x^2)^2-1))
Now simplify:
=-4/(xsqrt(16x^4-1)