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What is the difference between fibrinogen (fibrin) and platelets?

1 Answer
Jan 27, 2018


Platelet #-># a component of blood
Fibrin #-># a protein
Together they participate in forming a hemostatic clot.


Fibrinogen and fibrin are not the same thing.
Fibrinogen is a protein found in blood plasma. It converts to fibrin, under the influence of thrombin#->#enzyme, and it is involved in the formation of blood clots.
Fibrin that is formed from fibrinogen is a non-globular protein involved in the clotting of blood. Fibrin is stabilized by an enzyme called factor XIII that crosslinks fibrin.
Here you can see the whole process from fibrinogen to a crosslinked fibrin mesh.

Platelets are components of blood which participate in blood clotting.Their function is to stop bleeding.

Here is a really good animation of the team work between fibrin and platelets.