Question

What is the difference between myoglobin, foetal haemoglobin and adult haemoglobin?

Answer 1

• See below:

Explanation:

• MYOGLOBIN :

What is Myoglobin??????

- lt is an iron and oxygen binding protein found in muscle tissues .

STRUCTURE OF MYOGLOBIN:

• lt has more affinity for oxygen.

• But it has only one `Fe^2` group , the curve obtained will be hyperbolic , than being sigmoid.

• FETAL HAEMOGLOBIN:
• What is Fetal haemoglobin??????

• Fetal haemoglobin has higher affinity for `O_2` because it binds BPG less strongly ( 2,3 Biphosphoglyceric acid ) . BPG act as negitive regulator , it enhances `CO_2` binding and prevents `O_2` binding.
• ADULT HAEMOGLOBIN:
• What is Adult haemoglobin????
• The most common haemoglobin type is Tetramer. It has 4 subunits:
  -2 alpha
  -2 beta
  These subunits are non covalently bonded.
  -

When p`O_2` is low, Hb- F can carry upto 30% more `O_2` than maternal Hb-A . Therefore, oxygen - haemoglobin curve for fetal haemoglobin will appear on the left side.

• Oxygen dissociation curve for all the three terms:

Hope this will help u........