What is the Henderson-Hasselbalch equation?

1 Answer
Apr 17, 2014

The Henderson-Hasselbalch equation is an equation that determines the pH pf a buffer.

Acid Buffers

For a solution of a weak acid and its conjugate base,

HA + H₂O ⇌ H₃O⁺ + A⁻

pH = #pK_a + log("[A⁻]"/"[HA]")#

Base Buffers

For a solution of a weak base and its conjugate acid,

B+ H₂O ⇌ BH⁺ + OH⁻

pOH = #pK_b + log("[BH⁺]"/"[B]")#