Question

What is the rationale for the fat cell theory of obesity?

Answer 1

The rationale for the fat cell theory of obesity is the observation of obese and also adopted children who were born to obese couples, who then became obese in spite of proper nutrition.

Explanation:

The fat cell theory is based in indicators that obesity can be traced to genetics among many other factors that result in "excessive" weight. "Excessive" weight can be hard to judge, because for some people, extra weight is as normal as extra height, or bigger or smaller hands. Obesity occurs when the extra weight becomes a threat to a person's health or well-being.

As a result of genetics, a descendant might be born with the extra fat cells, or with the genetic structure to acquire them by hyperplasia where the body gains fat cells during childhood and adolescence. To make matters worse, the adult body can increase the size of the fat cells by hypertrophy. Controlling fat cell production must begin early in life.

Once formed, the fat cells cannot be lost by diet or exercise. They can only be reduced in size. There have been some graphic documentaries showing the removal of hardened stomach fat by surgery as the only means left.

A study of obese parents and children is here:
http://news.stanford.edu/news/2004/july21/med-obesity-721.html

There are more details here:
https://www.sciencedaily.com/releases/2008/05/080509133100.htm

Reasons for difficulty in loosing weight and keeping it off are here:
http://www.healthguideinfo.com/healthy-eating/p20099/