What is the structural formula for serine with a pH of 4?
1 Answer
Read over this, and then see if you can draw the structure. You should have the structure of serine memorized.
Well, serine has two pKas to consider; the carboxyl and the amine pKa's (
#"pH" = "pK"_a + log((["A"^])/(["HA"]))#
Here we see that

if
#["HA"] < ["A"^()]# , then#(["A"^])/(["HA"]) > 1# and#log((["A"^])/(["HA"])) > 0# . Thus,#"pH" > "pK"_a# and the solution is basic with respect to the proton whose#"pK"_a# is given. 
if
#["HA"] > ["A"^()]# , then#(["A"^])/(["HA"]) < 1# and#log((["A"^])/(["HA"])) < 0# . Thus,#"pH" < "pK"_a# and the solution is acidic with respect to the proton whose#"pK"_a# is given.
Clearly, since
 The solution is basic with respect to the carboxyl group.
 The solution is acidic with respect to the amine group.
Hence, the carboxyl group is DEprotonated, and the amine group is protonated. Their charges are thus