Which type of mutation is responsible for sickle cell anemia?

1 Answer
Dec 3, 2015

Point mutation


Sickle cell anemia is a Autosomal recessive disorder associated with 11th chromosome.
In this disorder , there occurs point mutation at the 6th position of beta chain of haemoglobin, glutamic acid is replaced by valine which results in the formation of abnormal haemoglobin which causes deformation in the shape of RBC.enter image source here