# Why is aromaticity important?

Jul 18, 2014

Aromaticity is important because it makes molecules more stable.

Aromatic compounds play important roles in biochemistry and in industry.

IMPORTANT BIOCHEMICAL AROMATICS

Aromatic compounds play key roles in the biochemistry of all living things

Amino Acids

Amino acids are the building blocks of proteins. Four of them — histidine, phenylalanine, tyrosine, and tryptophan — are aromatic.

Nucleotides

Five nucleotides make up the sequence of the genetic code in DNA and RNA. All five — adenine, guanine, cytosine, thymine, and uracil — have aromatic rings. They contribute to the stability of DNA and RNA.

Heme

The molecule heme contains a ring system with 22 π electrons. According to Hückel's 4$n$ + 2 rule, it is aromatic ($n$ = 5).

IMPORTANT INDUSTRIAL AROMATICS

Important commercial aromatic compounds include benzene, toluene, 1,2-, and 1,4-dimethylbenzene.

These in turn are the starting materials for compounds such as styrene, phenol, aniline, polyesters, and nylon.