Question

Question #adfe4

Answer 1

Both cannot be considered catalyst. There are 8 catalysts. Seven intermediates are produced from one enzyme. Meanwhile, aconitase enzyme is used for two intermediates.

Explanation:

1. citrate synthase
2. aconitase
3. isocitrate dehydrogenase
4. α-ketoglutarate dehydrogenase
5. succinyl-CoA synthetase
6. Succinate dehydrogenase
7. fumarase
8. malate dehydrogenase

Basically, there are:-
1) four dehydrogenases (oxidation process) - involved in hydrogen abstraction
2) one bond forming enzymes (synthetase)
3) one hydration enzyme. And one enzyme is involved in a dehydration+hydration step (a form of isomerization).

http://crystal.res.ku.edu/taksnotes/Biol_638/notes/chp_16.pdf