What exactly makes the creation of a vaccine against malaria difficult?

What features of the lifecycle of the pathogen that causes malaria make the development of an effective vaccine especially difficult?

1 Answer
Feb 24, 2018

It is to be noted that vaccine preparation is aimed against those diseases which are contagious in nature so people are at high risk for epidemics,but malaria doesn't spread from man to man directly,so just by preventing the mosquito to bite,this disease can be prevented.

Moreover, prophylactic antibiotic treatment against malaria is found to be beneficial wherever required.

Drugs used for prophylaxis against malaria are, Mefloquine and Doxycycline.

Thank you !