How many stereogenic centres are there in Tetracycline?
1 Answer
Apr 9, 2018
Consider tetracycline, an antibiotic primarily used to treat skin and acne infections,
We're looking to count the number of chirality centers in this compound, or those carbons with four different connections.
Note the carbons with only three connections, the
I highlighted in red the stereochemistry in the molecule (with implied hydrogens where applicable),
Hence, if we count the carbons that have those red groups coming off, we count: