Question

Question #e7547

Answer 1

Here's my explanation.

Explanation:

Conformers

Conformers ( or conformational isomers) are isomers that can be interconverted by rotation about single bonds.

For example, the staggered and eclipsed forms of ethane are conformers, because they can be interconverted by rotation about the `"C-C"` single bond.

Invertomers

Invertomers are isomers that can be interconverted by inversion of an atom that has a lone pair of electrons.

(From Kshitij IIT JEE)

Amines undergo rapid inversion of configuration, so the enantiomers cannot be separated.

However, in rigid cyclic amines, the energy barrier for inversion is often high enough that the invertomers can be separated at room temperature.

For example, the inversion barrier for 1-chloro-2-methylaziridine is so high that the cis and trans isomers can be separated by gas chromatography at 25 °C.