A woman with type O blood has children with her husband who is type AB. What percent of their children would you expect to have type O blood?

1 Answer
Jan 31, 2018

None of the children of woman can have O blood group.

Explanation:

Blood groups A,B, AB and O are determined by the presence of antigen A and B. O blood group does not have any antigen and that is why person with O blood group is universal donor.

Antigen A is produced due to the presence of dominant allele I A in homozygous (IA IA) or heterozygous (IA i) state. A person with genotypes IA IA or IA i will have A blood group.

Antigen B is produced due to the presence of dominant allele I B in homozygous (IB IB) or heterozygous (IB i) state. A person with genotypes IB IB or IB Ii will have B blood group.

The recessive allele i does not produce any antigen. A person with recessive allele in homozygous state (ii) will not produce any antigen and will have O blood group.

The woman in question has O blood group and has genotype (ii).
Her husband has AB blood group and thus has genotype IA IB.

The child inherites one allele each from either parent. Thus all the children will receive recessive allele (i) from mother and either IA or IB from the father.

None of the children can be homozygous for recessive allele (ii). Thus none of the children of this couple will have O blood group.