# Does alcohol react with the Grignard reagents?

Jan 4, 2016

Absolutely: alcohol is a protic solvent.

#### Explanation:

$R - M g X + D O - R ' \rightarrow R - D + R ' O - M g X$

The reaction represents the reaction of a Grignard reagent. $R - M g X$, with deuterio-alchohol, R'O""^2H; this is a way of introducing a deuterium label into an alkyl chain. I would have got the same organic product had I reacted the Grignard with ${D}_{2} O$.