Does alcohol react with the Grignard reagents?

1 Answer
anor277
Jan 4, 2016

Absolutely: alcohol is a protic solvent.

Explanation:

#R-MgX + DO-R' rarr R-D + R'O-MgX#

The reaction represents the reaction of a Grignard reagent. #R-MgX#, with deuterio-alchohol, #R'O""^2H#; this is a way of introducing a deuterium label into an alkyl chain. I would have got the same organic product had I reacted the Grignard with #D_2O#.

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