How can interferons inhibit viral replication?
Interferons help activate immune and other cells when a pathogen is sensed, and these other cells will destroy or contain the pathogen.
Interferons are signaling proteins that are released when pathogens are detected in the bloodstream. They then trigger the protective mechanisms of immune cells and promote the release of antigens. For example, a type 1 interferon will activate molecules than prevent the correct production of viral DNA. This will render the virus harmless because it can no longer replicate and spread.