How do ribosomes differ from lysosomes?
Ribosomes manufacture proteins from mRNA. Lysosomes are organelles that are involved in destruction (or "lysing") of nefarious substances or weary organelles.
They are pretty different components of the cell. Lysosomes for one are organelles, meaning that they have their own membranes. Hence, they are only found in eukaryotic cells. They are also responsible mainly for destruction. They can destroy worn out organelles, whole cells, and sometimes foreign invaders.
On the other hand, ribosomes are not organelles. They are one of the few components that you find in the cells of all organisms, irrespective of type. They are for converting mRNA into proteins in a process called translation.
So in a sense, you could say that they are components with opposite functions (one builds, the other destroys).
Hope that helped :)