How does a deletion mutation differ from a substitution mutation?

1 Answer
Apr 27, 2017

Deletion mutation is deletion of a base from the genetic sequence, which changes the codon reading frame beyond the point of mutation.
Substitution mutation involves replacement of a base (e.g. one purine) by another base (either purine or pyrimidine).


Deletion mutation will lead to frameshift : Substitution mutation will not.