How many Good's buffer agents exist?

1 Answer
May 6, 2016

Answer:

There are 20 Good buffers.

Explanation:

Named after Norman Good, they are all physiological buffers with #"p"K_a# values ranging from 6.1 to 8.5.

The buffers, with their #"p"K_a# values, are:

  1. MES: #"2-("N"-morpholino)ethanesulfonic acid"#, 6.15

  2. ADA: #N"-(2-acetamido)iminodiacetic acid"#, 6.62

  3. PIPES: #"piperazine-"N,N′"-bis(2-ethanesulfonic acid)"#, 6.82

  4. ACES: #N"-(2-acetamido)-2-aminoethanesulfonic acid"#, 6.88

  5. MOPSO: #"3-("N"-morpholinyl)-2-hydroxypropanesulfonic acid"#, 6.95

  6. Cholamine chloride: #("CH"_3)_3 stackrel(+)("N")"CH"_2"CH"_2"NH"_2, "Cl"^"-"#, 7.10

  7. BES: #N,N"-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid"#, 7.17

  8. MOPS: #"3-("N"-morpholino)propanesulfonic acid"#, 7.20

  9. TES: #N"-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid"#, 7.40

  10. HEPES: #"4-(2-hydroxyethyl)-1-piperazinylethanesulfonic acid"#, 7.48

  11. DIPSO: #N,N"-bis(2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid"#, 7.60

  12. TAPSO:# "3-["N"-tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid"#, 7.60

  13. Acetamidoglycine: #"CH"_3"CONHNHCH"_2"COOH"#, 7.7

  14. POPSO: #"piperazine-"N,N′"-bis(2-hydroxypropanesulfonic acid)"#, 7.85

  15. HEPPSO: #"4-(2-hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid)"#, 7.85

  16. HEPPS: #"3-[4-(2-hydroxyethyl)-1-piperazinyl]propanesulfonic acid"#, 8.00

  17. Tricine: #N"-[tris(hydroxymethyl)methyl)]glycine"#, 8.15

  18. Glycinamide: #"NH"_2"CH"_2"CONH"_2#, 8.20

  19. Bicine: #N,N"-bis(2-hydroxyethyl)glycine"#, 8.35

  20. TAPS: #N"-tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid"#, 8.44