Is there a requirement for the stereochemistry of the starting material in E1 reactions? Why?
There is no stereochemical requirement for the starting material in
This causes formation of the less stable alkene in cyclohexane compounds such as (
This requirement does not exist in
The β C-H bond must be able to overlap the p orbital of the carbocation , so the β C-H bond must be axial.
We can always do a ring flip, so we can always form the more stable product, 1,2-dimethylcyclohexane.