Question

What does aspirin do to your stomach?

Answer 1

It may cause some gastrointestinal complications such as diarrhea, nausea, gastric ulceration and bleeding.

Explanation:

Aspirin - or Ascetylsalicylic Acid (ASA) - is a well-known medication from the family of the Nonsteroidal Anti-inflammatory Drugs (NSAIDs) . Despite the benefit of taking these drugs, they may have adverse effects on the gastrointestinal tract.

First, their acidic properties irritate the mucosa, which is a problem on its own. Additionally, it biochemically inhibits COX-1 and COX-2 , which regulate the production of prostagladins . Low levels of prostaglandins in the stomach usually increase the tract's acideness levels and decrease the production of mucus, which utterly results in diarrheas, nauseas and vomit, peptic ulceration and stomach bleeding.