What does X inactivation do in females?

1 Answer
Oct 18, 2016

X inactivation is a process by which one of the copies of the X chromosome present in the female mammals is inactivated.

Explanation:

The inactivated X chromosome condenses into a compact structure called as the he Barr body.

Unlike the gene poor Y chromosome , the X chromosome contains over 1000 genes, that are essential for proper development and cell viability. Females carry two copies of X chromosomes , resulting in a double dose of X linked genes. To correct this imbalance mammalian females have evolved the unique mechanism of X chromosome inactivation.

Transcriptionally silent Barr bodies maintain gene equality between makes ( XY ) and females ( XX ) .