What happens if microtubules and microfilaments are absent in the cell?

1 Answer
Jan 3, 2016

Some microtubules are using in protein transport (by kinesin and dynein). Even organelles like mitochondria is transported via microtubule network. So protein transport and organelle movement will get disrupted


For example, when nocodazole was used to disrupt microtubules,
directional mitochondrial motility was impaired

Florian Fuchs (2002) Interaction of mitochondria with microtubules in the filamentous fungus Neurospora crassa

Mariusz Karbowski, et. al., (2000) Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells